Phytosome- Valuable Phyto-Phospholipid Carriers.
نویسندگان
چکیده
منابع مشابه
Planterosomes: a Potential Phyto-phospholipid Carriers for the Bioavailability Enhancement of Herbal Extracts
Planterosomes, term “PLANTERO” means plant while “SOME” means celllike. A novel emerging technique applied to phytopharmaceutical for the enhancement of bioavailability of herbal extract for medicinal applications. Since the two major limiting factors for molecules to pass the biological membrane for their absorption in the blood stream mainly includes lipid solubility and molecular sizes. Ther...
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Phytoconstituents have been used in medicine science since ancient times due to their various pharmacological actions. But most of them (like flavanoids, terpenoids) are low in lipid solubility and have large molecular size due to complex multiple ring structure, causing poor absorption and poor bioavailability via oral route. The phytosome system of drug delivery results in increased bioavaila...
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Among various phospholipid-mediated drug delivery systems (DDS) suitable for topic and oral administration, phytosome technology represents an advanced innovation, widely used to incorporate standardized bioactive polyphenolic phytoconstituents into phospholipid molecular complexes. In order to extend their potential therapeutic efficiency also to other routes of administration, we proposed a n...
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For good bioavailability, natural products must have a good balance between hydrophilicity (for dissolving into the gastro-intestinal fluids) and lipophilicity (to cross lipidic biomembranes). Many phytoconstituents like glycosilated polyphenolics have good water solubility, but are, nevertheless, poorly absorbed[1] because of their large size, incompatible with a process of passive diffusion a...
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The beneficial effects of Greenselect Phytosome, a proprietary lecithin formulation of a caffeine-free green tea catechin extract, were evaluated in a controlled registry study on 50 asymptomatic subjects borderline for metabolic syndrome factors and with increased plasma oxidative stress. After 24 weeks of intervention, improvement in weight, blood lipid profile, and blood pressure positioned ...
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ژورنال
عنوان ژورنال: Journal of Current Pharma Research
سال: 2014
ISSN: 2230-7834,2230-7842
DOI: 10.33786/jcpr.2014.v05i01.008